1950년대, 체 게바라와 피델 카스트로는 군부 독재로 고통받는 민중을 위해 쿠바로 향한다. 혁명을 위해 목숨을 건 게릴라전을 펼치던 체 게바라는 수도 아바나를 점령하기 위한 마지막 관문인 산타클라라에서 최후의 작전을 감행하는데…
Benicio del Toro
Ernesto Che Guevara
Demián Bichir
Fidel Castro
Rodrigo Santoro
Raúl Castro
Santiago Cabrera
Camilo Cienfuegos
Julia Ormond
Lisa Howard
Ramon Fernandez
Hector
Oscar Isaac
U.N. Interpreter
María Isabel Díaz Lago
María Antonia
Yul Vazquez
Alejandro Ramirez
Jsu Garcia
Jorge Sotus
Marisé Álvarez
Vilma Espín
Elvira Mínguez
Celia Sánchez
Unax Ugalde
Vaquerito
Andres Munar
Joel Iglesias Leyva
Miguel Ángel Suárez
Army Doctor
Alfredo de Quesada
Israel Pardo
Roberto Urbina
Guile Pardo
Monique Gabriela Curnen
Secretary
Sam Robards
Tad Szulc
Euriamis Losada
Carlos
Catalina Sandino Moreno
Aleida March
Xavier Morales
Esteban's accomplice
José Brocco
Ovidio Díaz Rodríguez
Leonardo Castro Sitiriche
Army medic
Yamil Collazo
Enrique Oltuski
Ektor Rivera
Rafael Mompié
Aris Mejias
Carmen
Edgar Ramírez
Ciro Redondo García
Gerardo Albarrán
Police Officer
Guillermo Ríos
Comandante Gómez Calderón
Ramiro 'Ramir' Delgado Ruiz
Wounded Rebel (uncredited)
Mateo Gómez
Cuban Diplomat #1